Orygen is the National Centre of Excellence in Youth Mental Health. It is a world leader in the research and knowledge which focuses on mental ill-health in young people. It delivers cutting-edge research, policy development, innovative clinical services, and evidence-based training and education. This ensures the continuous improvement in the treatment and care of Australian youth experiencing mental ill-health. It has developed new models and a more positive approach to the prevention and treatment of mental disorders. Mental ill-health continues to be a leading health issue facing young people today.